Wittig horner reaction
The Horner–Wadsworth–Emmons reaction (or HWE reaction) is the chemical reaction of stabilized phosphonate carbanions with aldehydes (or ketones) to produce predominantly E-alkenes.
In 1958, Leopold Horner published a modified Wittig reaction using phosphonate-stabilized carbanions.William S. Wadsworth and William D. Emmons further defined the reaction.
In contrast to phosphonium ylides used in the Wittig reaction, phosphonate-stabilized carbanions are more nucleophilic but less basic. Likewise, phosphonate-stabilized carbanions can be alkylated. Unlike phosphonium ylides, the dialkylphosphate salt byproduct is easily removed by aqueous extraction.
Several reviews have been published.

This is an excerpt from the article Wittig horner reaction from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
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WITTIG REACTION | MECHANISM |…
The reaction of an aldehyde or ketone with a phosphonium ylide to an alkene and a phosphine oxide is known as Wittig reaction or Wittig Olefination reaction.
www.adichemistry.com/organic/namedreactions/wittigreaction/wittig-reaction-1.html
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Horner-Wadsworth-Emmons Reaction - Home |…
"Olefin Synthesis with Organic Phosphonate Carbanions," J. Boutagy and R. Thomas, Chem. Rev. 1974, 74, 87. "Synthetic Applications of Phosphoryl Stabilized Anions," W ...
www.chem.wisc.edu/areas/reich/chem547/1-carbonyl%7B19%7D.htm
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Wittig-Horner Reaction - Organic Chemistry Portal
Wittig-Horner Reaction Horner-Wadsworth-Emmons Reaction. The reaction of aldehydes or ketones with stabilized phosphorus ylides (phosphonate ...
www.organic-chemistry.org/namedreactions/wittig-horner-reaction.shtm
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Horner–Wadsworth–Emmons reaction - Wikipedia, the free ...
In 1958, Leopold Horner published a modified Wittig reaction using phosphonate -stabilized carbanions. William S. Wadsworth and William D. Emmons further ...
en.wikipedia.org/wiki/Horner%E2%80%93Wadsworth%E2%80%93Emmons_reaction
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Wittig–Horner reaction - Wikipedia, the free encyclopedia
Wittig–Horner reaction. From Wikipedia, the free encyclopedia. (Redirected from Wittig-Horner reaction) Redirect page. Jump to: navigation, search ...
en.wikipedia.org/wiki/Wittig-Horner_reaction
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Olefination Reactions
Olefination Reactions. - Wittig Reaction (Phosphorous ylides). - Horner- Wadsworth-Emmons Reaction (Phosphonates). - McMurry Coupling (Titanium ...
www.uni-heidelberg.de/institute/fak12/OC/bunz/lectures/mecha/Olefination_Reactions.pdf
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Sample Quiz for the Wittig-Horner Reaction Experiment
Sample Quiz for the Wittig-Horner Reaction Experiment. 1) When you do the Wittig-Homer reaction, you willbecome quite aware of tl1e stench of one of tl1e ...
orgchem.colorado.edu/Labs/Quizzes/Wittig.pdf
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Efficient Total Synthesis of Piceatannol via (E)-Selective Wittig ...
Wittig–Horner reaction is demonstrated with six steps in overall 40% yield ... Wittig–Horner reaction of diethyl phosphonate with aldehyde showed a superior ...
www.tandfonline.com/doi/pdf/10.1080/00397910802528944
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Horner-Wadsworth-Emmons Olefination
In 1958, Horner disclosed a modified Wittig reaction employing phosphonate- stabilized carbanions; the scope of the reaction was further defined by Wadsworth ...
www.chem.harvard.edu/groups/myers/handouts/15_Horner-Wadsworth.pdf
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Mechanism of the Phospha‐Wittig–Horner Reaction
May 7, 2013 ... The Swedish Research Council, the Göran Gustafsson Foundation, COST action 0802 PhoSciNet, and Uppsala University (U3MEC molecular ...
onlinelibrary.wiley.com/doi/10.1002/anie.201301469/abstract
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Wittig horner reaction in science
Mechanism of the Phospha-Wittig-Horner Reaction.
May 7, 2013 ... Mechanism of the Phospha-Wittig-Horner Reaction. ... Department of Chemistry, Ångström Laboratories, Uppsala University, Box 523, 751 20 ...
Mechanism of the Phospha‐Wittig–Horner Reaction
May 7, 2013 ... Mechanism of the Phospha-Wittig–Horner Reaction† ... COST action 0802 PhoSciNet, and Uppsala University (U3MEC molecular electronics ...
[PDF]Synthesis of Bis-styrylbenzene derivatives via Wittig-Horner reaction
Wittig-Horner reaction. Joseph K. Wray. University of Nevada, Las Vegas. Tae Soo Jo. University of Nevada, Las Vegas. Pradip K. Browmik. University of ...
Revisiting the Phospha-Wittig-Horner Reaction
Revisiting the Phospha-Wittig - Horner Reaction. Department: Uppsala University , Disciplinary Domain of Science and Technology, Chemistry, Department of ...
Heterocycles from Intramolecular Wittig, Horner and Wadsworth ...
Oct 9, 2012 ... University of Huddersfield. Information ... Heterocycles from Intramolecular Wittig, Horner and Wadsworth-Emmons Reactions. Tools. - Tools. + ...
[PDF]Efficient Total Synthesis of Piceatannol via (E)-Selective Wittig ...
Hallym University, Chuncheon, Korea. Abstract: Efficient and practical total synthesis of piceatannol via (E)-selective. Wittig–Horner reaction is demonstrated ...
[PDF]Enantioselective Wittig-Horner Reaction in the Solid State
Department of Industrial Chemistry, Faculty of Engineering, Ehime University, Matsuyama 790, Japan ... Summary: Wittig-Horner reactions in the solid state of ...
[PDF]Synthesis of Stilbene by Wittig & Wadsworth-Emmons
... the Wittig and. Horner-Wadsworth-Emmons Reactions ... 590) - Wittig reaction for the synthesis of stilbene. Part B (p. ... University of Heidelberg. Nobel Prize - ...
Dipeptide vinyl sultams: Synthesis via the Wittig–Horner reaction ...
The Open University ... Dipeptide vinyl sultams: Synthesis via the Wittig–Horner reaction and activity against papain, falcipain-2 and Plasmodium falciparum ...
Mechanism of the Phospha-Wittig-Horner Reaction. | ResearchGate
Publication » Mechanism of the Phospha-Wittig-Horner Reaction.. ... Department of Chemistry, Ångström Laboratories, Uppsala University, Box 523, 751 20 ...
Books on the term Wittig horner reaction
Organic Mechanisms: Reactions, Stereochemistry and Synthesis
Organic Mechanisms: Reactions, Stereochemistry and Synthesis
Reinhard Bruckner, Michael Harmata, 2010
The Wittig-Horner reaction performed in a single operation, as described, is flawed by the lack of stereocontrol. That's because the phosphorylated lithium alkoxide D is formed without diastereoselectivity. So the alkene E is also formed without ...
Microscale Organic Laboratory: with Multistep and Multiscale Syntheses
Microscale Organic Laboratory: with Multistep and Multiscale Syntheses
Dana W. Mayo, Ronald M. Pike, David C. Forbes, 2010
An important modification (often called the Horner–Wadsworth–Emmons reaction ) of the Wittig reaction makes use of phosphonate esters, RPO(OR)2. It is highly stereoselective for the formation of E-alkenes. The re- action and mechanism are ...
New trends in green chemistry
New trends in green chemistry
V. K.. Ahluwalia, M.. Kidwai, 2004
Olefin Scheme 21 1n the above reaction the ylide is unstable and is generated in situ for reaction with the carbonyl compound. A modification of the above reaction , known as the Wittig-Horner reaction or Homer- Wadsworth-Emmons reaction ...
Organic Reaction Mechanisms, 2008
Organic Reaction Mechanisms, 2008
A. C. Knipe, 2011
Several important named elimination reactions have been reviewed: Chugaev, 32Ramberg-Backlund,3'3 Zaitsev,34 and Krapcho decarboxylation? ... reported. 36 Quantum, mechanical investigation of the Horner-Wadsworth-Emmons reaction of benzyl pyridyl ketone suggested a possible role ... The cobalt(ll) porphyrin complex has been found to be an efficient catalyst for the Wittig-type olefination of acyl ...
Comprehensive Organic Functional Group Transformations: Synthesis ...
Comprehensive Organic Functional Group Transformations: Synthesis ...
Alan Roy Katritzky, Otto Meth-Cohn, Gordon William Kirby, 1995
90 Phosphonate. diethyl dibromomethyl. use in Wittig Homer reaction, 745 Phosphonate. diethyl dichloromethyl. use in Wittig horner reaction. 740 Phosphonate. diethyl difluoromethyl. use in Wittig horner reaction. 734 Phosphonate. diethyl ...
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Wittig horner reaction
Wittig Reaction | TOM CHEMICAL
TOM CHEMICAL
al20130426.wordpress.com/2013/04/29/wittig-reaction/
Cheap essay writers: The Wittig Reaction - Lab Report
INTRODUCTION The purpose of this experiment is to synthesize trans-9-(2-phenylethenyl) anthracene from benzyltriphenylphosphonium chloride and 9-anthraldehyde by means of the reaction machine recognized as the Wittig Reaction. The Wittig Reaction allows the pill pusher to synthesize phosphoranes in the lab with relative ease.
cheap-essaywriters-blog.blogspot.com/2013/04/the-wittig-reaction-lab-report.html
Wittig-Horner Reaction/Horner-Wadsworth-Emmons Reaction - maillhf的日志 - 网易博客
Wittig-Horner Reaction/Horner-Wadsworth-Emmons Reaction,maillhf的网易博客,网易博客,
maillhf.blog.163.com/blog/static/314321372007103112952469/
Pharma Entrance: Named reactions –to be studied for gpat and niper
Named reactions –to be studied for gpat and niper Acetoacetic Ester Synthesis Acyloin Condensation Aldol Addition + Aldol Condensation Appel Reaction Arbuzov Reaction = Michaelis-Arbuzov Reaction Arndt-Eistert Synthesis Azo Coupling Baeyer-Villiger Oxidation Balz-Schiemann Reaction = Schiemann Reaction Bamford-Stevens Reaction Barton Decarboxylation Barton-McCombie Reaction (Barton Desoxygenation) Baylis-Hillman Reaction Beckmann Rearrangement Benzilic Acid Rearrangement Benzoin Condensation Bergman Cyclization Birch Reduction Bouveault-Blanc Reduction Buchwald-Hartwig Cross Coupling Reaction Cadiot-Chodkiewicz Coupling Cannizzaro Reaction Chugaev Reaction Claisen Condensation Claisen Rearrangement Clemmensen Reduction Cope Elimination Cope Rearrangement Corey-Seebach Reaction Criegee Reaction Curtius Rearrangement Delépine Reaction De Mayo Reaction Dess-Martin Oxidation Diazotisation and Azo Coupling Dieckmann Condensation Diels-Alder Reaction Di-ð-Methane Rearrangement Dötz Reaction Eglinton Reaction Ene Reaction = Alder-Ene Reaction Jacobsen Epoxidation Ester Pyrolysis Favorskii Reaction Finkelstein Reaction Friedel-Crafts Acylation Friedel-Crafts Alkylation Gabriel Synthesis Gattermann-Koch Reaction Glaser Coupling and Hay Coupling Grignard Reaction Grob Fragmentation Grubbs Olefin Metathesis Haloform Reaction Heck Reaction Hell-Volhard-Zelinsky Reaction Henry Reaktion Hofmann Elimination Hofmann's Rule Horner-Wadsworth-Emmons Reaction Hunsdiecker Reaction Hydroboration Ireland-Claisen Rearrangement Knoevenagel Condensation Kolbe Reaction Kolbe-Schmitt Reaction Kumada–Negishi Coupling Leuckart–Wallach (Leuckart) Reaction Malonic Ester Synthesis Mannich Reaction Markovnikov's Rule McMurry Reaction Meerwein-Ponndorf-Verley Reduction Michael Addition Mitsunobu Reaction Mukaiyama Aldol Addition Negishi Coupling Norrish-Type I and II Nozaki-Hiyama Coupling Nucleophilic Substitution (SN1 / SN2) Oppenauer Oxidation Oxy-Cope Rearrangement Paterno-Büchi Reaction Pauson-Khand Reaction Perkin Reaction Peterson Olefination Pinacol Coupling Reaction Pinacol Rearrangement Prilezhaev Epoxidation Reformatsky Reaction Ritter Reaction Robinson Annulation Rosenmund Reduction Sakurai Reaction (Hosomi Sakurai) Sandmeyer Reaction Sanger’s Reagent Saytzeff's Rule Schiemann Reaction Schmidt Reaction Schotten-Baumann Reaction Sharpless Epoxidation and Dihydroxylation Simmons-Smith Reaction Sonogashira Coupling Staudinger Reaction Stille Coupling Strecker Synthesis Suzuki Coupling Swern Oxidation Tebbe Olefination Thorpe Reaction Tishhenko Reaction Ullmann Reaction Vilsmeier Reaction Wacker-Tsuji Oxidation Willgerodt-Kindler Reaction Williamson Synthesis Wittig Olefination Wittig Rearrangement Wittig-Horner Reaction Wohl-Ziegler Reaction Wolff Rearrangement Wolff-Kishner Reduction Wurtz Reaction Wurtz-Fittig Reaction.
pharmaentrance.blogspot.com/2012/05/named-reactions-to-be-studied-for-gpat.html
An Improved Protocol for the Aldehyde Olefination Reaction Using (bmim) () as Reaction Medium
Journal of Chemistry is a peer-reviewed, open access journal that publishes original research articles as well as review articles in all areas of chemistry.
www.hindawi.com/journals/chem/2013/439673/
"A Systematic Study of the Effects of Naphthalene and Anthracene Substi" by Patrick Lynch, Luke O'Neill et al.
The systematic synthesis of poly(phenylvinylene) (PPV) derivatives by the Wittig-Horner reaction is reported. The phenyl units of the PPV structure are methodically substituted by naphthyl and anthryl units to form a homologous series of structures. The 2,6 attachment of the vinylene linkage on the anthryl ring provides novel structures that have not been reported before due to their synthetic inaccessibility. The introduction of naphthyl units results in a hypsochromatic shift in the absorption and emission spectra, while the introduction of anthryl units leads to a bathochromatic shift relative to the naphthalene structures. The observed structural variation of the spectroscopic properties is explained in terms of a combination of the increased conjugation of the substituent acene units and the decreased electronic contribution across the vinyl linkage.
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Application of the diastereoselective photodeconjugation of α,β-unsaturated esters to the synthesis of gymnastatin H
Application of the diastereoselective photodeconjugation of α,β-unsaturated esters to the synthesis of gymnastatin H
www.beilstein-journals.org/bjoc/content/7/1/21
Curly Arrow: Colourful Chemistry
I'm doing lots of new chemistry in my new job which is great. Since I started my career as an organic chemist more or less everything has been supposed to be colourless or white.
curlyarrow.blogspot.com/2007/12/colourful-chemistry.html
About Basics Chemistry: Wittig Reaction
basicschemistry.blogspot.com/2013/04/wittig-reaction.html
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