White (mutation)
White Gene, abbreviated w, was the first sex-linked mutation ever discovered in the fruit fly Drosophila melanogaster. In 1910 Thomas Hunt Morgan and Lilian Vaughan Morgan collected a single male white-eyed mutant from a population of Drosophila melanogaster fruit flies, which usually have dark brick red eyes. Upon crossing this male with wild-type female flies, they found that the offspring did not conform to the expectations of Mendelian inheritance. The first generation (the F1) produced 1,237 red-eyed offspring and three white-eyed flies, all males. The second generation (the F2) produced 2,459 red-eyed females, 1,011 red-eyed males, and 782 white-eyed males. Further experimental crosses led them to the conclusion that this mutation was somehow physically connected to the "factor" that determined gender in Drosophila. Morgan named this trait white gene, now abbreviated w. Flies carrying the white allele/ white gene are frequently used to introduce high school and college students to genetics. The protein coded by white functions as an ATP-binding cassette (ABC) transporter. It carries the precursors of the red and brown eye color pigments, guanine and tryptophan, into the developing eyes during pupation. The human version of white is ABCG1, and is involved in transporting lipids and cholesterol into cells.

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Scientists Find A DNA Change That Accounts For White Skin
Dec 16, 2005 ... Scientists said yesterday that they have discovered a tiny genetic mutation that largely explains the first appearance of white skin in humans ...
www.washingtonpost.com/wp-dyn/content/article/2005/12/15/AR2005121501728.html
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White (mutation) - Wikipedia, the free encyclopedia
White, abbreviated w, was the first sex-linked mutation ever discovered in the fruit fly Drosophila melanogaster. In 1910 Thomas Hunt Morgan and Lilian ...
en.wikipedia.org/wiki/White_(mutation)
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How a Genetic Mutation Led to the White "Race"
Jan 29, 2011 ... Penn State University researchers have found that a genetic mutation led to the rise of white skin when humans left Africa 20000 to 50000 ...
racerelations.about.com/b/2011/01/29/how-a-genetic-mutation-led-to-the-white-race.htm
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Fruit fly genetics :: DNA from the Beginning
It all started when we found our first useful fruit fly mutation. Flies normally have red eyes but in January, 1910, we found a male with white eyes. We immediately ...
www.dnaftb.org/10/animation.html
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What is the physiological basis of the white-eyed mutation in ...
The normal eye color for Drosophila flies is red. The white eye mutation is a mutation in the eye color gene, causing the eyes to become colorless ...
answers.yahoo.com/question/index?qid=20081110201620AAVyd3n
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Exhibit: Mutant Fruit Flies - Drosophila Genetics | Exploratorium
The fruit flies in this exhibit show just a few of the mutations that occur in natural fruit ... They have a defect in their "white" gene, which normally produces the red ...
www.exploratorium.edu/exhibits/mutant_flies/mutant_flies.html
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Mutations in the white gene of Drosophila melanogaster affecting ...
Biochim Biophys Acta. 1999 Jul 15;1419(2):173-85. Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye ...
www.ncbi.nlm.nih.gov/pubmed/10407069
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White grapes arose through the mutation of two similar and adjacent ...
Plant J. 2007 Mar;49(5):772-85. White grapes arose through the mutation of two similar and adjacent regulatory genes. Walker AR, Lee E, Bogs J, McDavid DA, ...
www.ncbi.nlm.nih.gov/pubmed/17316172
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Genes and Mutations - Complementation Testing - NDSU
A wide array of spontaneous mutations have been studied. These experiments demonstrated that five genes (white, ruby, vermillion, garnet and carnation) ...
www.ndsu.edu/pubweb/~mcclean/plsc431/mutation/mutation5.htm
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White Tiger Genetic Secret Unveiled: Single Mutation In Single ...
May 23, 2013 ... Making a regular tiger into a white tiger is as simple as changing a single gene.
www.ibtimes.com/white-tiger-genetic-secret-unveiled-single-mutation-single-gene-removes-orange-color-photos-1276755
Search results for "White (mutation)"
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White (mutation) in science
Scientists Find A DNA Change That Accounts For White Skin
Dec 16, 2005... tiny genetic mutation that largely explains the first appearance of white skin ... Leaders of the study, at Penn State University, warned against ...
PLOS Genetics: Global Dissemination of a Single Mutation ...
Global Dissemination of a Single Mutation Conferring White Pericarp in Rice ... Affiliation: Department of Plant Breeding and Genetics, Cornell University, Ithaca, ...
Fruit fly genetics :: DNA from the Beginning
In 1904, I started the "Fly" lab at Columbia University to study genetic variations. Many of ... Males have white eyes when they inherit the mutant gene on the X ...
Research Unplugged: The mutation that became white skin | Penn ...
May 18, 2012 ... Penn State University · Penn State University ... Research Unplugged: The mutation that became white skin ...
A de novo mutation in KIT causes white spotting in a subpopulation ...
Nov 8, 2012 ... A de novo mutation in KIT causes white spotting in a subpopulation of German Shepherd dogs. A. K. Wong1,5,; A. L. Ruhe1,; K. R. Robertson1, ...
Multifocal White Matter Lesions Associated with the D313Y Mutation ...
Affiliation: Department of Neurology, University Hospital Muenster, Muenster, ... ( 2013) Multifocal White Matter Lesions Associated with the D313Y Mutation of ...
White, Thomas W - Department of Physiology & Biophysics | Stony ...
Stony Brook University ... The Cx26-G45E mutation displays increased hemichannel activity in a ... N.A. Levit, G. Meşe, M.-G. R. Basaly and T.W. White ( 2011).
How a Genetic Mutation Led to the White "Race"
Jan 29, 2011 ... Penn State University researchers have found that a genetic mutation led to the rise of white skin when humans left Africa 20000 to 50000 ...
'White tiger numbers can be increased without inbreeding' | The Hindu
May 24, 2013 ... 'White tiger numbers can be increased without inbreeding' ... to the scientists from Peking University, Beijing, an A477V point mutation in a ...
Books on the term White (mutation)
Doves: Everything About Housing, Health, Nutrition, and Breeding
Doves: Everything About Housing, Health, Nutrition, and Breeding
Gayle Soucek, 2006
White tail and white rump mutations: Can manifest in any of the previously discussed colors, including wild. The mutations that cause white tail and white rump are the same, and the only difference is the amount of white displayed. White tails ...
Insect Development: Insect Morphogenesis, Molting and Metamorphosis
Insect Development: Insect Morphogenesis, Molting and Metamorphosis
Lawrence I. Gilbert, 2009
As dominant-acting neomorphs, that do not depend on preexisting mutations, they are directly useful in almost all host strains. When compared to the white eye color marker in Drosophila, the enhanced green fluorescent protein (EGFP) gene ...
Mutation breeding: theory and practical applications
Mutation breeding: theory and practical applications
A. M. van Harten, 1998
Another subject touched upon by Evenari concerns the question whether back mutations from white to green occur. The, prevailing, positive answer to this question has been challenged by Bergann & Bergann (1983) who, for periclinal ...
Genetics
Genetics
Daniel L. Hartl, 2011
The white transporter is located in the pigment-producing cells in the eye, and its target molecule is one of the key precursors of the eye-color pigments; hence, flies with a mutant white transporter have white eyes. The question addressed by ...
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Blog posts on the term
White (mutation)
Today's white rice is mutation spread by early farmers, researchers say | Cornell Chronicle
Cornell Chronicle: Daily news from Cornell University
news.cornell.edu/stories/2007/08/todays-white-rice-mutation-spread-early-farmers
Scientists Find One Gene Responsible For All White Tigers | Popular Science
Science may not be totally sure how the tiger got its stripes, but at least
www.popsci.com/science/article/2013-05/scientists-find-one-gene-responsible-all-white-tigers
White tiger coat caused by single gene mutation: study | The Vietnam Times
vietnamtimes.com.vn/white-tiger-coat-caused-by-single-gene-mutation-study/
Mutations in Susceptibility Genes Common in Younger African American Women with Breast Cancer | American Renaissance
Genes help explain blacks' higher risk for breast cancer and lower survival rates.
www.amren.com/news/2013/06/mutations-in-susceptibility-genes-common-in-younger-african-american-women-with-breast-cancer/
FunTickle.me » We Tickle Your Funny Bone ! » A very Rare genetic Mutation: The black parents shocked when their son was born white with blond hair.
We Tickle Your Funny Bone !
funtickle.me/a-very-rare-genetic-mutation-the-black-parents-shocked-when-their-son-was-born-white-with-blond-hair/
Tiger, Tiger, Brilliant White
White tigers, despite the name, aren’t all white. These variants of the Bengal tiger are white with black or dark brown stripes, and they also have blue eyes, pink paw pads and a pink nose.
wildthings.sarahzielinski.com/blog/tiger-tiger-brilliant-white/
White tiger coat caused by single gene mutation: study — TalkVietnam
talkvietnam.com/2013/05/white-tiger-coat-caused-by-single-gene-mutation-study/
Why I Just Gave a Bunch of Old White Dudes Five Hundred Dollars | Emotional Mutation
A great WordPress.com site
unquietpirate.wordpress.com/2013/05/15/why-i-just-gave-a-bunch-of-old-white-dudes-five-hundred-dollars/
White tiger coat caused by single gene mutation: study — Vietnam Breaking News
vietnambreakingnews.com/2013/05/white-tiger-coat-caused-by-single-gene-mutation-study/
White tiger coat caused by single pigment gene mutation: Research | Team Zimbabwe
The spectacular white coats of white tigers are caused by a single change in a known pigment gene, a new study has found.The research, to be published in the June issue of Current Biology, might help ...
teamzimbabwe.org/white-tiger-coat-caused-by-single-pigment-gene-mutation-research/
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