Oximes
An oxime is a chemical compound belonging to the imines, with the general formula R1R2C=N O H, where R1 is an organic side chain and R2 may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime. O-substituted oximes form a closely related family of compounds. Amidoximes are oximes of amides with general structure RC(=NOH)(NRR').
Oximes are usually generated by the reaction of hydroxylamine and aldehydes or ketones. The term oxime dates back to the 19th century, a portmanteau of the words oxygen and imine.

This is an excerpt from the article Oximes from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
Images on Oximes
Preview image:
Original:
Search results from Google and Bing
1
1
1
Oxime - Wikipedia, the free encyclopedia
An oxime is a chemical compound belonging to the imines, with the general formula R1R2C=N O H, where R1 is an organic side chain and R2 may be ...
en.wikipedia.org/wiki/Oxime
2
>30
2
The role of oximes in the management of organophosphorus ...
The value of Oximes, however, is still a matter of controversy. Enthusiastic reports of outstanding antidotal effectiveness, substantiated by laboratory findings of ...
www.ncbi.nlm.nih.gov/pubmed/15181665
3
>30
3
Oximes - definition of Oximes by the Free Online Dictionary ...
Any of a group of compounds containing a CNOH group, formed by treating aldehydes or ketones with hydroxylamine. [ox(o)- + im(id)e.] oxime [ˈɒksiːm]. n.
www.thefreedictionary.com/Oximes
4
>30
4
Oximes - Nitrogen Compounds | Sigma-Aldrich
Oximes and O-substituted Oximes are prominent structural ...
www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16255373
5
>30
5
Structural Chemistry of Oximes - Crystal Growth & Design (ACS ...
May 9, 2013 ... Oximes (RR′C═N–OH) represent an important class of organic compounds with a wide range of practical applications, but a systematic ...
pubs.acs.org/doi/abs/10.1021/cg4005246
6
>30
6
Rule C-842 Oximes and Their Derivatives (Groups Containing One ...
842.1 - Compounds RHC=N-OH or , termed generic ally "Oximes", are named (a) by placing the word "oxime" after the name of the aldehyde RCHO or the ...
www.acdlabs.com/iupac/nomenclature/79/r79_583.htm
7
>30
7
Oxime Definition - Definition of Oxime - Chemistry - About.com
This is the definition of oxime. ... Oximes where R' is a hydrogen atom are called aldOximes. All other Oximes are called ketOximes. Chemistry Glossaries & ...
chemistry.about.com/od/dictionariesglossaries/g/Oxime-Definition.htm
8
>30
8
Oxime synthesis by oxidation or redox reaction
Recent Literature. In the presence of zinc oxide and without any additional organic solvents, Beckmann rearrangement of several ketones and aldehydes were ...
www.organic-chemistry.org/synthesis/C2N/oximes.shtm
9
>30
9
O-alkylation and arylation of Oximes, Hydroxylamines and related ...
Recent Literature. A direct preparation of O-substituted hydroxylamines from alcohols is described by O-alkylation of tert-butyl N-hydroxycarbamate with the ...
www.organic-chemistry.org/synthesis/C1O/o-alkylation.shtm
10
>30
10
Catalytic Enantioselective Iodoetherification of Oximes - Tripathi ...
Jul 3, 2013 ... Catalytic Enantioselective Iodoetherification of Oximes†. Chandra Bhushan Tripathi,; Prof. Dr. Santanu Mukherjee*. Article first published ...
onlinelibrary.wiley.com/doi/10.1002/anie.201304173/abstract
Search results for "Oximes"
Google: approx. 381.000
Oximes in science
Oximes - Nova - University of Newcastle
NOVA - University of Newcastle Research Online. ... Title: Oximes for acute organophosphate pesticide poisoning; Creator: Buckley, Nick A.; Eddleston, Michael; ...
Quinolines from oximes - DORAS - DCU
Jul 25, 2013 ... Quinolines from Oximes. Egan, Oliver James (1999) Quinolines from Oximes. PhD thesis, Dublin City University. Full text available as: ...
[PDF]Modification of Phenolic Oximes for Copper Extraction - Edinburgh ...
Since graduating from the University of Edinburgh in 2004 with a MChem. ... series of 5-alkyl-3-X-2-hydroxybenzaldehyde Oximes (X = a range of substituents ) is.
Five Experimental Bispyridinium Oximes in Comparison with the ...
Five Experimental Bispyridinium Oximes in Comparison with the Conventional Oximes Pralidoxime and Obidoxime: In Vivo Efficacy to Protect from ...
The role of oximes in the management of organophosphorus ...
... of Pharmacology and Toxicology, Ludwig-Maximilians-University, Munich, Germany. ... The value of Oximes, however, is still a matter of controversy.
Unequal Efficacy of Pyridinium Oximes in Acute Organophosphate ...
Milos P. Stojiljkovic, Department of Biochemistry, Pharmacology & Genetics, Odense University Hospital, University of Southern Denmark, Winsløwparken 19,  ...
Hydrolytic Stability of Hydrazones and Oximes - Wiley Online Library
Aug 19, 2008 ... Hydrolytic Stability of Hydrazones and Oximes† ... and Engineering Center at the University of Wisconsin-Madison (NSF DMR-0520527).
Oximes - ResearchGate
What is the latest and best method for preparing Oximes? Oximes are generally prepared ... Shahid Beheshti University of Medical Sciences. Alexey Sukhorukov.
[PDF]Efficacious Oxime for Organophosphorus Poisoning - African ...
University, PO Box 17666, AlAin, United Arab Emirate. Abstract ... oxime is a promising candidate to replace therapeutically available Oximes with respect to.
Books on the term Oximes
Comprehensive Organic Synthesis: Reduction
Comprehensive Organic Synthesis: Reduction
Barry M. Trost, Ian Fleming, 1991
spending to entry 4 afforded the five-membered isoxazolidine resulting from displacement of tosyl by the hydroxylamine oxygen.194 The reduction of O-acyl Oximes to 0-acylhydroxylamines also is accomplished under mild conditions with  ...
Oxime: Webster's Timeline History, 1894 - 2007
Oxime: Webster's Timeline History, 1894 - 2007
Icon Group International, 2010
Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, ge...
Oximes—Advances in Research and Application: 2012 Edition: ...
Oximes—Advances in Research and Application: 2012 Edition: ...
2012
cording to the authors of a study from Hradec Kralove, Czech Republic, “The influence of the combinations of Oximes on the reactivating and therapeutic efficacy of antidotal treament of acute sarin poisoning was evaluated in this study.
Studies of Oximes
Studies of Oximes
Janak Shukla, Sanjay Shah and Kartik Vyas, 2012
Dr. Janak R. Shukla, Ph.D : Hemchandracharya North Gujarat University, Patan. Principal at Shree C.N.P.F. Arts & D.N. Science College, Dabhoi, District: Vadodara, Gujarat.
Weapons of Mass Destruction
Weapons of Mass Destruction
In the case oftabun,the oxime TMB4 (the acronym for N,N'-trimethylene bis-[ pyridine-4- aldoxime bromide]) is more effective against tabun than is 2-PAM-Cl, for example. Other Oximes are being studied that can make up for deficiencies, ...
The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids (Patai's Chemistry of Functional Groups)
The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids (Patai's Chemistry of Functional Groups)
Zvi Rappoport and Joel F. Liebman, 2011
Focusing on an important class of compounds in organic synthesis, this text features contributions by leading experts, and delivers the quality expected from the “Patai Series.”
Handbook of Pesticide Toxicology
Handbook of Pesticide Toxicology
Robert I. Krieger, 2001
Insufficient oxime therapy also has been considered as a possible cause of the intermediate syndrome (Benson et al, 1992). However, such a hypothesis does not explain why the intermediate syndrome is not influenced by atropine or why ...
Chemical Warfare Agents: Toxicology and Treatment
Chemical Warfare Agents: Toxicology and Treatment
Dr Timothy T. Marrs, Robert L. Maynard, Frederick Sidell, 2007
Here, reactivating Oximes can be expected to act as specific antidotes. Search for suitable reactivators dates back to the early 1950s, starting with hydroxylamine and hydro xamic acids (Hobbiger, 1 963) . Later on, ketOximes and aldOximes ...
Advances in Heterocyclic Chemistry, Volume 107
Advances in Heterocyclic Chemistry, Volume 107
Alan R. Katritzky, 2012
Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how ...
Development of Google searches


Blog posts on the term
Oximes
IJMS | Free Full-Text | Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study
Acetylcholinesterase (AChE) reactivators were developed for the treatment of organophosphate intoxication. Standard care involves the use of anticonvulsants (e.g., diazepam), parasympatolytics (e.g., atropine) and Oximes that restore AChE activity. However, Oximes also bind to the active site of AChE, simultaneously acting as reversible inhibitors. The goal of the present study is to determine how oxime structure influences the inhibition of human recombinant AChE (hrAChE). Therefore, 24 structurally different Oximes were tested and the results compared to the previous eel AChE (EeAChE) experiments. Structural factors that were tested included the number of pyridinium rings, the length and structural features of the linker, and the number and position of the oxime group on the pyridinium ring.
www.mdpi.com/1422-0067/14/8/16882
exd https://sites.google.com/site/barbouroutletuksale/ cineplasty oximes
www.ibusinesstalk.co.uk/showthread.php?tid=84546
Chemoselective Protection of α-Ketoacids by Direct Annulations with Oximes - Organic Letters (ACS Publications)
pubs.acs.org/doi/abs/10.1021/ol100467t
IJMS | Free Full-Text | In Vitro Ability of Currently Available Oximes to Reactivate Organophosphate Pesticide-Inhibited Human Acetylcholinesterase and Butyrylcholinesterase
We have in vitro tested the ability of common, commercially available, cholinesterase reactivators (pralidoxime, obidoxime, methoxime, trimedoxime and HI-6) to reactivate human acetylcholinesterase (AChE), inhibited by five structurally different organophosphate pesticides and inhibitors (paraoxon, dichlorvos, DFP, leptophos-oxon and methamidophos). We also tested reactivation of human butyrylcholinesterase (BChE) with the aim of finding a potent oxime, suitable to serve as a “pseudocatalytic” bioscavenger in combination with this enzyme. Such a combination could allow an increase of prophylactic and therapeutic efficacy of the administered enzyme. According to our results, the best broad-spectrum AChE reactivators were trimedoxime and obidoxime in the case of paraoxon, leptophos-oxon, and methamidophos-inhibited AChE. Methamidophos and leptophos-oxon were quite easily reactivatable by all tested reactivators. In the case of methamidophos-inhibited AChE, the lower oxime concentration (10−5 M) had higher reactivation ability than the 10−4 M concentration. Therefore, we evaluated the reactivation ability of obidoxime in a concentration range of 10−3–10−7 M. The reactivation of methamidophos-inhibited AChE with different obidoxime concentrations resulted in a bell shaped curve with maximum reactivation at 10−5 M. In the case of BChE, no reactivator exceeded 15% reactivation ability and therefore none of the Oximes can be recommended as a candidate for “pseudocatalytic” bioscavengers with BChE.
www.mdpi.com/1422-0067/12/3/2077
Conversion of Oximes to Carbonyl Compounds with 2-Nitro-4,5-dichloropyridazin-3(2H)-one - The Journal of Organic Chemistry (ACS Publications)
pubs.acs.org/doi/abs/10.1021/jo902356e
Different hydrogen-bonding modes in two closely related oximes
scripts.iucr.org/cgi-bin/paper?dn3141
prosoduaki - The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids - download pdf ebook
prosoduaki.livejournal.com/18960.html
Life = Thinking: OXIMES CONTRAINDICATED IN CARBAMATE POISONING - AN ILLUSTRATION
PAM-pralidoxime OP organophosphate C carbamates E Estericsite A anionic site ache Acetyl Choline Esterase ENZYME REACTIVATORS like PRALIDOXIME can be used in OP POISONING but they are CONTRAINDICATED in CARBAMATE POISONING The site on which Oximes bind and reactivate the enzyme - ANIONIC SITE is occupied by carbamates (right side of fig) Where as it is free in organophosphate poisoning (left side of fig) OP - ESTERIC SITE ONLY C - ESTERIC + ANIONIC And also Oximes also has weak ache inhibitory action.
nishurs.blogspot.com/2011/05/oximes-contraindicated-in-carbamate.html
12